John Curci

John A. Curci, MD, FACS

  • Associate Professor of Surgery

Medical School

Yale University School of Medicine, New Haven, Conneticut, 1994

Post Doctoral Education

Residency: Surgery, Barnes-Jewish Hospital at Washington University School of Medicine, St. Louis, Missouri, 1999

Research Fellowship: Vascular, Washington University School of Medicine, St. Louis, Missouri, 1998

Clinical Fellowship: Vascular, Barnes-Jewish Hospital at Washington University School of Medicine, St. Louis, Missouri, 2003

Board Certifications

Vascular Surgery--Certified
General Surgery--Certified

Honors and Awards

Chairman, Research and Education Committee, Society for Vascular Surgery

Inducted into Alpha Omega Alpha, 1999

Samuel A. Wells Resident Research Award, Washington University School of Medicine, 1999

First prize, Resident Research Competition, Missouri Chapter, American College of Surgeons, 1997

Clinical Interests

Dr. Curci specializes in vascular surgery, endovascular surgery and heart disease. His areas of clinical interest include carotid and brachiocephalic artery diseases; aneurysmal, occlusive and embolic disease of the thoracic and abdominal aorta; mesenteric and renal vascular diseases; peripheral arterial diseases; surgery for hemodialysis and chronic venous access; venous insufficiency or ulceration; and abdominal aortic aneurysm (AAA).

Research Interests

National Heart, Lung and Blood Institute, NIH
American Heart Association
The Flight Attendants Medical Research Institute (FAMRI)

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital
John Cochran Veterans Administration Hospital

Patients Seen At

Center for Advanced Medicine
Heart and Vascular Center
4921 Parkview Place, Suite A, Floor 8
St. Louis, MO 63110
(314) 362-7406
Fax: (314) 747-3548

Barnes-Jewish West County Hospital
Professional Building 1
1040 N. Mason Rd
Suite 120
Creve Coeur, MO
(314) 362-7406

Contact Information

Washington University School of Medicine
Department of Surgery
Section of Vascular Surgery
Campus Box 8109
St. Louis, MO 63110
(314) 362-7406

Selected Publications

Duwayri Y, Vallabhaneni R, Kirby JP, Mueller MJ, Volshteyn O, Geraghty PJ, Sicard GA, Curci JA. Early Protection and Compression of Residual Limbs May Improve and Accelerate Prosthetic Fit: A Preliminary Study. Ann Vasc Surg. 2011 Nov 1. [Epub ahead of print]

Melman L, Chisholm PR, Curci JA, Arif B, Pierce R, Jenkins ED, Brunt LM, Eagon C, Frisella M, Miller K, Matthews BD. Differential regulation of MMP-2 in the gastrohepatic ligament of the gastroesophageal junction. Surg Endosc. 2010 Jul;24(7):1562-5.

Pratt B, Curci J. Arterial elastic fiber structure. Function and potential roles in acute aortic dissection. J Cardiovasc Surg (Torino). 2010 Oct;51(5):647-56. Review.

Curci JA. Digging in the "soil" of the aorta to understand the growth of abdominal aortic aneurysms. Vascular. 2009 May-Jun;17 Suppl 1:S21-9.

Hackmann AE, Rubin BG, Sanchez LA, Geraghty PA, Thompson RW, Curci JA. A randomized, placebo-controlled trial of doxycycline after endoluminal aneurysm repair. J Vasc Surg. 2008 Sep;48(3):519-26; discussion 526.

Curci JA, Fillinger MF, Naslund TC, Rubin BG; for the Excluder Bifurcated Endoprosthesis Investigators. Clinical trial results of a modified gore excluder endograft: comparison with open repair and original device design. Annals of Vascular Surgery. 2007;21(3):328-38. Epub 2007 Mar 7.

Bergoeing MP, Arif B, Hackmann AE, Ennis TL, Thompson RW, Curci JA. Cigarette smoking increases aortic dilatation without affecting matrix metalloproteinase-9 and -12 expression in a modified mouse model of aneurysm formation. Journal of Vascular Surgery. 2007;45(6):1217-1227. Epub 2007 Mar 29.

Buckley C, Wyble CW, Borhani M, Ennis TL, Kobayashi DK, Curci JA, Shapiro SD, Thompson RW. Accelerated enlargement of experimental abdominal aortic aneurysms in a mouse model of chronic cigarette smoke exposure. Journal of American College of Surgeons. 2004;199(6):896-903.

Curci JA, Thompson RW. Adaptive cellular immunity in aortic aneurysms: cause, consequence, or context? Journal of Clinical Investigation. 2004;114(2):168-171.

Liao S, Curci JA, Kelley BJ, Sicard GA, Thompson RW. Accelerated replicative senescence of medial smooth muscle cells derived from abdominal aortic aneurysms compared to the adjacent inferior mesenteric artery. Journal of Surgical Research. 2000;92(1):85-95.

Liao S, Miralles M, Kelley BJ, Curci JA, Borhani M, Thompson RW. Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin converting enzyme inhibitors. Journal of Vascular Surgery. 2001;33(5):1057-1064.

Pyo R, Lee JK, Shipley JM, Curci JA, Mao D, Ziporin SJ, Ennis TL, Shapiro SD, Senior RM, Thompson RW. Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms. Journal of Clinical Investigation. 2000;105(11):1641-1649.

Curci JA, Mao D, Bonner D, Allen BT, Rubin BG, Reilly JM, Sicard GA, Thompson RW. Preoperative treatment with doxycycline reduces aortic wall expression and activation of matrix metalloproteinases in patients with abdominal aortic aneurysms. Journal of Vascular Surgery. 2000;31(2):325-342.

Curci JA, Petrinec D, Liao S, Golub LM, Thompson RW. Pharmacologic suppression of experimental abdominal aortic aneurysms: a comparison of doxycycline and four chemically modified tetracyclines. Journal of Vascular Surgery. 1998;28(6):1082-1093.

Curci JA, Liao S, Huffman MD, Shapiro SD, Thompson RW. Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms. Journal of Clinical Investigation. 1998;102(11):1900-1910.

Pub Med page for John A. Curci, M.D., F.A.C.S.